They conclude: "When patients stop taking metformin, physicians should consider inquiring more closely about revulsion to the odor of the medication. Trial of a film-coated, extended-release formulation may be a reasonable approach in such cases. Annals of Internal Medicine article Subscription required. Which one of the following next steps is most appropriate in the care of a year-old man with type 2 diabetes and a history of tuberculosis exposure who is found to have a mm area of induration 48 hours after a purified protein derivative test is placed on his forearm?
October 17, Surgery, General. What You Can Do. Share This:. Originally Published February 19, Save Your Favorites. Sign Up Already have an account? An extended release generic version, coated to make it dissolve more slowly, solved the problem.
A second man refused to ever take metformin again, even coated formulations, they said. Perhaps a trial of a film-coated, ER formulation may be a reasonable approach. This is usually a non-issue, although the occasional patient declines metformin for this reason.
Those patients can then take the more expensive brandname products, although our peculiar reimbursement system is such that this may require inordinate effort! Follow EndocrineToday.
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