The pounds themselves can cause heart muscle injury. By , one in five adults may have heart failure. Injured heart muscle cells release an enzyme called troponin T. Doctors measure this in the blood when someone is suspected of having a heart attack. Here are three ways that obesity contributes to heart disease — and what you can do to take control of your health and combat not only obesity, but heart disease too!
Fortunately, there are some steps you can take to lose weight, get healthy and reduce your risk of developing heart disease. The number one thing any obese individual, especially those with a family history of cardiovascular disease, should do to get healthy is to exercise regularly and eat a nutritious, balanced diet.
Talk with your doctor about creating a diet and exercise plan that works best for you based on your current goals and health status. Gut microbiota also have a role in promoting increased adiposity. Proinflammatory signaling generated in response to bacterial lipopolysaccharide may affect neurobehavioral brain centers and adversely affect adipocyte function, leading to adiposopathy and increased risk for metabolic disease.
Adiposopathy refers to the pathogenic enlargement of adipose cells and adipose tissue that results in anatomic and functional abnormalities, leading to metabolic disease and increased cardiovascular disease risk. Specifically, adiposopathy is defined as adipocyte and adipose tissue dysfunction caused by positive caloric balance and sedentary lifestyle in genetically and environmentally susceptible individuals. These anatomic and pathophysiologic changes result in various clinical manifestations, including high blood glucose, insulin resistance, hypertension, adiposopathic dyslipidemia, metabolic syndrome, atherosclerosis and a host of other pathologies.
Obesity promotes systemic inflammation, and inflammation can drive adipogenesis. Chronic systemic inflammation, along with increased accumulation of epicardial adipose tissue has been observed in people with obesity. Systemic inflammation promotes the expression of a proinflammatory phenotype in epicardial fat, particularly the adipose tissue surrounding the coronary arteries. Chronic inflammation and accumulation of epicardial fat is strongly associated with the presence, severity and progression of coronary artery disease, independent of visceral adiposity.
They secrete adiponectin, which minimizes inflammation and fibrosis in the coronary arteries and myocardium. In contrast, epicardial fat in obese people is more prone to lipolysis, leading to release of fatty acids and reactive inflammation. In obesity, adiponectin secretion from epicardial fat is reduced and proinflammatory adipokines are released, promoting infiltration of macrophages, destruction of microvascular systems and activation of fibrotic pathways Figure.
Avoid added sugars, highly processed foods , and fried foods. A study published in May in the journal Preventive Medicine found that adults ages 18 to 35 with BMI between 25 and 40 who participated in a weight-loss program lost an average of By subscribing you agree to the Terms of Use and Privacy Policy. Health Topics. Health Tools. Heart Disease.
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